Comparison · NCT01840072-9efb97ed
Active Antihypertensive Treatment vs Usual Care: Mortality
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Active Antihypertensive Treatment vs Usual Care: Mortality. Trial comparisons, record NCT01840072-9efb97ed. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01840072-9efb97ed
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0342 | 0.0271 | 0.0431 | wilson | |
| Risk in group 2 | 0.0272 | 0.0209 | 0.0353 | wilson | |
| Risk difference, group 1 minus group 2 | 0.00703 | -0.00377 | 0.018 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.26 | 0.885 | 1.79 | log | |
| Odds ratio, group 1 over group 2 | 1.27 | 0.882 | 1.82 | log | |
| Number needed to treat, for one more participant with the outcome on Active Antihypertensive Treatment than on Usual Care | 142 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: usual care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Active Antihypertensive Treatment | Active antihypertensive treatment~Active antihypertensive treatment: Initial antihypertensive treatment with angiotensin-converting enzyme inhibitors (Enalapril) and/or calcium channel blockers as second line medication; and/or diuretics as third line medications. Based on patients' baseline BP level, the first-line medication (intravenous Enalapril) can be used alone, or in combination with second-line medication (calcium channel blocker), and third-line medication (diuretics) to achieve the target systolic BP lowering by 10% to 25% within the first 24 hours after randomization and to achieve systolic BP below 140 mm Hg and diastolic BP below 90 mm Hg and maintain this BP level afterwards during the hospitalization. | 68 | 1,988 | OG000 |
| Group 2 | Usual Care | Discontinue all home BP medications. | 54 | 1,987 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Mortality
- Description
- Those patients who are still alive at hospital discharge will be contacted by telephone to set up a follow-up clinical visit. Information on clinical deaths will be obtained.
- Time frame
- 3 months
- Population
- All participants followed at 3-month posttreatment follow-up visit
Source ClinicalTrials.gov
Trial
- Title
- China Antihypertensive Trial in Acute Ischemic Stroke
- NCT number
- NCT01840072
- Phases
- NA
- Conditions
- Ischemic Stroke
- Interventions
- Active antihypertensive treatment
- Lead sponsor
- Tulane University
- Results first posted
- 2014-11-20
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01840072?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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