Comparison · NCT01874535-553fedb6
4 Week Group vs 8 Week Group: The Rates of Complete Symptom Relief
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. 4 Week Group vs 8 Week Group: The Rates of Complete Symptom Relief. Trial comparisons, record NCT01874535-553fedb6. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01874535-553fedb6
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.734 | 0.67 | 0.79 | wilson | |
| Risk in group 2 | 0.781 | 0.719 | 0.833 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0468 | -0.129 | 0.0365 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.94 | 0.842 | 1.05 | log | |
| Odds ratio, group 1 over group 2 | 0.775 | 0.491 | 1.22 | log | |
| Number needed to treat, for one fewer participant with the outcome on 4 Week Group than on 8 Week Group | 21.4 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | 4 Week Group | Patients with Los Angeles A and B esophagitis prescribed with esomeprazole (40 mg)daily~Esomeprazole 40 mg: Comparison of 4-weeks weeks initial treatment duration of esomeprazole 40 mg per day on the rate of symptom relapse and sustained healing of esophagitis in patients with symptomatic erosive esophagitis | 152 | 207 | OG000 |
| Group 2 | 8 Week Group | Patients with Los Angeles A and B esophagitis prescribed with esomeprazole (40 mg)daily~Esomeprazole 40 mg: Comparison of 8-weeks initial treatment duration of esomeprazole 40 mg per day on the rate of symptom relapse and sustained healing of esophagitis in patients with symptomatic erosive esophagitis | 157 | 201 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- The Rates of Complete Symptom Relief
- Description
- Rate of complete symptom relief (CSR) at the end of initial treatment phase
- Time frame
- at the 20 weeks after the end of initial treatment.
- Population
Source ClinicalTrials.gov
Trial
- Title
- Rate of Complete Symptom Relief, Prevention of Symptom Relapse: Grades A and B Esophagitis of Esomeprazole Therapy
- NCT number
- NCT01874535
- Phases
- PHASE4
- Conditions
- Erosive Esophagitis
- Interventions
- Esomeprazole 40 mg
- Lead sponsor
- Chang Gung Memorial Hospital
- Results first posted
- 2018-09-04
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01874535?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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