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Comparison · NCT01891344-deaths

Part 1 Overall vs Part 2 Overall: deaths from any cause

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Part 1 Overall vs Part 2 Overall: deaths from any cause. Trial comparisons, record NCT01891344-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01891344-deaths

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.00980.002690.035wilson
Risk in group 20.06270.040.097wilson
Risk difference, group 1 minus group 2-0.0529-0.0879-0.019newcombe hybrid score
Risk ratio, group 1 over group 20.1560.03670.666log
Odds ratio, group 1 over group 20.1480.03390.645log
Number needed to treat, for one fewer death from any cause on Part 1 Overall than on Part 2 Overall18.911.452.7from the risk difference interval

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Part 1 OverallAll patients who participated in Part 1 who received at least one dose of rucaparib2204EG000
Group 2Part 2 OverallAll patients who participated in Part 2 who received at least one dose of rucaparib18287EG001

Harm

What it counts
Total, all-cause mortality
Time frame
Adverse events were reported from the time informed consent was obtained until 28 days after last dose of study drug, approximately 5 years.

Source ClinicalTrials.gov

Trial

Title
A Study of Rucaparib in Patients With Platinum-Sensitive, Relapsed, High-Grade Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (ARIEL2)
NCT number
NCT01891344
Phases
PHASE2
Conditions
Ovarian Cancer, Epithelial Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer
Interventions
Oral rucaparib
Lead sponsor
pharmaand GmbH
Results first posted
2021-07-13

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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