Comparison · NCT01891344-sae
Part 1 Overall vs Part 2 Overall: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Part 1 Overall vs Part 2 Overall: serious adverse events. Trial comparisons, record NCT01891344-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01891344-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.265 | 0.209 | 0.329 | wilson | |
| Risk in group 2 | 0.321 | 0.269 | 0.377 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0559 | -0.135 | 0.0266 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.826 | 0.622 | 1.1 | log | |
| Odds ratio, group 1 over group 2 | 0.763 | 0.513 | 1.14 | log | |
| Number needed to treat, for one fewer participant with a serious adverse event on Part 1 Overall than on Part 2 Overall | 17.9 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Part 1 Overall | All patients who participated in Part 1 who received at least one dose of rucaparib | 54 | 204 | EG000 |
| Group 2 | Part 2 Overall | All patients who participated in Part 2 who received at least one dose of rucaparib | 92 | 287 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- Adverse events were reported from the time informed consent was obtained until 28 days after last dose of study drug, approximately 5 years.
Source ClinicalTrials.gov
Trial
- Title
- A Study of Rucaparib in Patients With Platinum-Sensitive, Relapsed, High-Grade Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (ARIEL2)
- NCT number
- NCT01891344
- Phases
- PHASE2
- Conditions
- Ovarian Cancer, Epithelial Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer
- Interventions
- Oral rucaparib
- Lead sponsor
- pharmaand GmbH
- Results first posted
- 2021-07-13
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01891344?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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