Comparison · NCT01918371-sae
Patients With RVO vs Patients With DME: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Patients With RVO vs Patients With DME: serious adverse events. Trial comparisons, record NCT01918371-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01918371-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0727 | 0.0421 | 0.123 | wilson | |
| Risk in group 2 | 0.0769 | 0.0445 | 0.13 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0042 | -0.0652 | 0.0554 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.945 | 0.438 | 2.04 | log | |
| Odds ratio, group 1 over group 2 | 0.941 | 0.41 | 2.16 | log | |
| Number needed to treat, for one fewer participant with a serious adverse event on Patients With RVO than on Patients With DME | 238 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Patients With RVO | Patients with retinal vein occlusion (RVO) receiving anti-VEGF injection(s) (ranibizumab, bevacizumab or aflibercept) in accordance with standard of care practices. This is a retrospective chart review study. | 12 | 165 | EG000 |
| Group 2 | Patients With DME | Patients with diabetic macular edema (DME) receiving anti-VEGF injection(s) (ranibizumab, bevacizumab or aflibercept) in accordance with standard of care practices. This is a retrospective chart review study. | 12 | 156 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- Up to 4 Years
Source ClinicalTrials.gov
Trial
- Title
- A Retrospective Study of Anti-Vascular Endothelial Growth Factor (VEGF) Injections for Retinal Vein Occlusion or Diabetic Macular Edema
- NCT number
- NCT01918371
- Phases
- Conditions
- Retinal Vein Occlusion, Macular Edema
- Interventions
- Anti-VEGF
- Lead sponsor
- Allergan
- Results first posted
- 2016-05-26
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01918371?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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