Comparison · NCT01925014-0d147a27
Low-dose CT vs Standard-dose CT: Diagnostic Confidence in Diagnosing and Ruling Out Appendicitis: Indeterminate Interpretation (Grade 3)
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Low-dose CT vs Standard-dose CT: Diagnostic Confidence in Diagnosing and Ruling Out Appendicitis: Indeterminate Interpretation (Grade 3). Trial comparisons, record NCT01925014-0d147a27. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01925014-0d147a27
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0233 | 0.0167 | 0.0324 | wilson | |
| Risk in group 2 | 0.0371 | 0.0285 | 0.0482 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0138 | -0.0267 | -0.00126 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.628 | 0.411 | 0.961 | log | |
| Odds ratio, group 1 over group 2 | 0.619 | 0.4 | 0.959 | log | |
| Number needed to treat, for one fewer participant with the outcome on Low-dose CT than on Standard-dose CT | 72.5 | 37.5 | 793 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Low-dose CT | 2 millisievert | 34 | 1,459 | OG000 |
| Group 2 | Standard-dose CT | 8 millisievert or lower | 53 | 1,429 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Diagnostic Confidence in Diagnosing and Ruling Out Appendicitis: Indeterminate Interpretation (Grade 3)
- Description
The frequency of indeterminate CT interpretation (grade 3). Grade 1 denotes appendicitis definitely absent; grade 2, appendicitis probably absent; grade 3, indeterminate for the presence of appendicitis; grade 4, appendicitis probably present; and grade 5, appendicitis definitely present.
- Time frame
- 3 months after CT
- Population
- Patients with incomplete reference standards were not included in these analyses. Intention-to-treat.
Source ClinicalTrials.gov
Trial
- Title
- Low vs. Standard Dose CT for Appendicitis Trial
- NCT number
- NCT01925014
- Phases
- NA
- Conditions
- Appendicitis
- Interventions
- Diagnostic CT with low-dose radiation, Diagnostic CT with standard-dose radiation
- Lead sponsor
- Kyoung Ho Lee, MD
- Results first posted
- 2019-01-31
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01925014?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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