Comparison · NCT01925014-85ba4ab3
Low-dose CT vs Standard-dose CT: Prevalence of Non-perforated Appendicitis
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Low-dose CT vs Standard-dose CT: Prevalence of Non-perforated Appendicitis. Trial comparisons, record NCT01925014-85ba4ab3. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01925014-85ba4ab3
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.223 | 0.203 | 0.244 | wilson | |
| Risk in group 2 | 0.252 | 0.231 | 0.274 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0293 | -0.0593 | 0.000781 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.884 | 0.778 | 1 | log | |
| Odds ratio, group 1 over group 2 | 0.85 | 0.72 | 1 | log | |
| Number needed to treat, for one fewer participant with the outcome on Low-dose CT than on Standard-dose CT | 34.1 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Low-dose CT | 2 millisievert | 342 | 1,535 | OG000 |
| Group 2 | Standard-dose CT | 8 millisievert or lower | 388 | 1,539 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Prevalence of Non-perforated Appendicitis
- Description
The percentage (i.e., prevalence) of non-perforated appendicitis among all randomized cases. In January, 2016, when more than 2000 patients were enrolled, the data and safety monitoring board noted a between-group imbalance in the number of appendectomies. Because of the concern that such an imbalance might potentially jeopardize the comparability for the prespecified endpoints, the study protocol was amended to adopt the following additional secondary endpoints, which were assessed among all randomly assigned patients: the number of appendectomies, number of negative appendectomies, prevalence of perforated appendicitis, and prevalence of non-perforated appendicitis.
- Time frame
- 1 week after surgery
- Population
- Intention-to-treat.
Source ClinicalTrials.gov
Trial
- Title
- Low vs. Standard Dose CT for Appendicitis Trial
- NCT number
- NCT01925014
- Phases
- NA
- Conditions
- Appendicitis
- Interventions
- Diagnostic CT with low-dose radiation, Diagnostic CT with standard-dose radiation
- Lead sponsor
- Kyoung Ho Lee, MD
- Results first posted
- 2019-01-31
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01925014?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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