Comparison · NCT01942694-f10155b1
Vitamin D (Cholecalciferol) vs Placebo: Time to Development of Diabetes
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Vitamin D (Cholecalciferol) vs Placebo: Time to Development of Diabetes. Trial comparisons, record NCT01942694-f10155b1. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01942694-f10155b1
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.242 | 0.219 | 0.267 | wilson | |
| Risk in group 2 | 0.267 | 0.242 | 0.292 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0246 | -0.0592 | 0.0101 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.908 | 0.792 | 1.04 | log | |
| Odds ratio, group 1 over group 2 | 0.878 | 0.732 | 1.05 | log | |
| Number needed to treat, for one fewer participant with the outcome on Vitamin D (Cholecalciferol) than on Placebo | 40.7 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Vitamin D (Cholecalciferol) | One vitamin D pill daily~Vitamin D (Cholecalciferol): Vitamin D (Cholecalciferol) 4000 IU, administered as 1 soft-gel pill daily by mouth. | 293 | 1,211 | OG001 |
| Group 2 | Placebo | One pill daily~Placebo: Administered as one soft-gel pill daily by mouth | 323 | 1,212 | OG000 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Time to Development of Diabetes
- Description
New-onset diabetes was based on annual glycemic testing of fasting plasma glucose, glycated hemoglobin, and 2-hour post-load plasma glucose and semiannual testing of fasting plasma glucose and glycated hemoglobin. If two or three of the glycemic measures met the 2010 ADA thresholds for diabetes, the participant was considered to have met the diabetes outcome. When only the measure for fasting plasma glucose or glycated hemoglobin met the threshold, confirmatory testing was performed for the positive measure within 8 weeks. If only the measure for 2-hour post-load plasma glucose met the threshold, then a 75-g oral glucose tolerance test to reassess all three glycemic measures was repeated. If the repeat measure was positive or both fasting plasma glucose and glycated hemoglobin were positive (in the case of a repeat oral glucose tolerance test), than the participant was considered to have met the diabetes outcome.
- Time frame
- Approximately 48 months
- Population
Source ClinicalTrials.gov
Trial
- Title
- Vitamin D and Type 2 Diabetes Study
- NCT number
- NCT01942694
- Phases
- NA
- Conditions
- Prediabetes, Type 2 Diabetes
- Interventions
- Vitamin D (Cholecalciferol), Placebo
- Lead sponsor
- Tufts Medical Center
- Results first posted
- 2020-09-09
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01942694?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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