Comparison · NCT01961297-8d0e747e
Spasmodic Dysphonia vs Spasmodic Dysphonia/Voice Tremor: Number of Participants Who Reported Positive Effects.
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Spasmodic Dysphonia vs Spasmodic Dysphonia/Voice Tremor: Number of Participants Who Reported Positive Effects. Trial comparisons, record NCT01961297-8d0e747e. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01961297-8d0e747e
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.739 | 0.535 | 0.875 | wilson | |
| Risk in group 2 | 0.909 | 0.722 | 0.975 | wilson | |
| Risk difference, group 1 minus group 2 | -0.17 | -0.384 | 0.0611 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.813 | 0.617 | 1.07 | log | |
| Odds ratio, group 1 over group 2 | 0.283 | 0.0504 | 1.59 | log | |
| Number needed to treat, for one fewer participant with the outcome on Spasmodic Dysphonia than on Spasmodic Dysphonia/Voice Tremor | 5.88 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Spasmodic Dysphonia | Participants with Spasmodic Dysphonia (SD) given oral administration of a single dose of sodium oxybate (1.0-1.5 gm) | 17 | 23 | OG000 |
| Group 2 | Spasmodic Dysphonia/Voice Tremor | Participants with Spasmodic Dysphonia/Voice Tremor (SD/VT) given oral administration of a single dose of sodium oxybate (1.0-1.5 gm) | 20 | 22 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Number of Participants Who Reported Positive Effects.
- Description
- Number of participants who had reported positive effects of at least one alcohol drink on their voice symptoms
- Time frame
- Day 1
- Population
- Only alcohol-responsive participants were in this analysis which is 23 from the SD group and 22 from the SD/VT group.
Source ClinicalTrials.gov
Trial
- Title
- Voice Tremor in Spasmodic Dysphonia: Central Mechanisms and Treatment Response
- NCT number
- NCT01961297
- Phases
- PHASE2
- Conditions
- Spasmodic Dysphonia, Voice Tremor
- Interventions
- Sodium oxybate
- Lead sponsor
- Kristina Simonyan
- Results first posted
- 2017-11-22
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01961297?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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