Comparison · NCT01988402-sae
Allopurinol vs Sugar Pill (Placebo): serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Allopurinol vs Sugar Pill (Placebo): serious adverse events. Trial comparisons, record NCT01988402-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01988402-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0625 | 0.0111 | 0.283 | wilson | |
| Risk in group 2 | 0.105 | 0.0294 | 0.314 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0428 | -0.258 | 0.191 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.594 | 0.0591 | 5.96 | log | |
| Odds ratio, group 1 over group 2 | 0.567 | 0.0466 | 6.9 | log | |
| Number needed to treat, for one fewer participant with a serious adverse event on Allopurinol than on Sugar Pill (Placebo) | 23.4 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Allopurinol | Patients in this arm receive allopurinol, 100 mg daily for 14 days and then 200 mg daily for 14 days~allopurinol | 1 | 16 | EG000 |
| Group 2 | Sugar Pill (Placebo) | Patients in this arm receive one placebo (sugar) pill per day for 14 days then 2 placebo pills for 14 days.~Placebo (sugar pill) | 2 | 19 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- 28 days
Source ClinicalTrials.gov
Trial
- Title
- Does Allopurinol Prolong a Treated, Acute Gout Flare?
- NCT number
- NCT01988402
- Phases
- PHASE4
- Conditions
- Gout
- Interventions
- allopurinol, Placebo (sugar pill)
- Lead sponsor
- 59th Medical Wing
- Results first posted
- 2015-01-05
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01988402?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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