Expectant Management vs Elective Induction of Labor: Composite of Severe Neonatal Morbidity and Perinatal Mortality
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.054 | 0.0465 | 0.0626 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.0432 | 0.0365 | 0.0509 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | 0.0108 | 0.0000414 | 0.0217 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 1.25 | 1 | 1.57 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 1.27 | 1 | 1.6 | log | ClinicalTrials.gov | |
| Number needed to treat, for one more participant with the outcome on Expectant Management than on Elective Induction of Labor | 92.2 | 46 | 24,100 | from the risk difference interval | ClinicalTrials.gov |
Groups 2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | Expectant Management | Expectant management (unless a medical indication arises) until at least 40 weeks 5 days. | 164 | 3,037 | OG000 | ClinicalTrials.gov |
| Group 2 | Elective Induction of Labor | Elective induction of labor between 39 weeks 0 days and 39 weeks 4 days~Elective Induction of Labor: Women randomized to induction of labor will undergo induction via oxytocin at 39 weeks 0 days to 39 weeks 4 days. Those with an unfavorable cervix (modified Bishop score \< 5) will first undergo cervical ripening (method left to the discretion of the patient's physician) in conjunction with or followed by oxytocin stimulation unless a contraindication arises. | 132 | 3,059 | OG001 | ClinicalTrials.gov |
Outcome 5
| Field | Value | Source |
|---|---|---|
| Type | PRIMARY | ClinicalTrials.gov |
| Title | Composite of Severe Neonatal Morbidity and Perinatal Mortality | ClinicalTrials.gov |
| Description | Includes any one of:~* Perinatal death~* Need for respiratory support within 72 hours after birth~* Apgar score of 3 or less at 5 minutes~* Hypoxic-ischemic encephalopathy~* Seizure~* Infection (confirmed sepsis or pneumonia)~* Meconium aspiration system~* Birth trauma (bone fracture, neurologic injury or retinal hemorrhage)~* Intracranial or subaleal hemorrhage~* Hypotension requiring vasopressor support | ClinicalTrials.gov |
| Time frame | delivery through 72 hours after birth | ClinicalTrials.gov |
| Population | The analysis was intent to treat. | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | A Randomized Trial of Induction Versus Expectant Management | ClinicalTrials.gov |
| NCT number | NCT01990612 | ClinicalTrials.gov |
| Phases | NA | ClinicalTrials.gov |
| Conditions | Labor and Delivery | ClinicalTrials.gov |
| Interventions | Elective Induction of Labor | ClinicalTrials.gov |
| Lead sponsor | The George Washington University Biostatistics Center | ClinicalTrials.gov |
| Results first posted | 2019-01-25 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT01990612?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.