Comparison · NCT01993667-cef21e72
Acetazolamide Normal Dose vs Acetazolamide Low Dose: Number of Participants With Side Effects
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Acetazolamide Normal Dose vs Acetazolamide Low Dose: Number of Participants With Side Effects. Trial comparisons, record NCT01993667-cef21e72. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01993667-cef21e72
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.171 | 0.081 | 0.327 | wilson | |
| Risk in group 2 | 0.184 | 0.0922 | 0.334 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0128 | -0.188 | 0.168 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.931 | 0.346 | 2.5 | log | |
| Odds ratio, group 1 over group 2 | 0.916 | 0.275 | 3.05 | log | |
| Number needed to treat, for one fewer participant with the outcome on Acetazolamide Normal Dose than on Acetazolamide Low Dose | 78.2 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Acetazolamide Normal Dose | Experimental : Acetazolamide 125 mg twice daily~Acetazolamide: Administration of low dose acetazolamide | 6 | 35 | OG000 |
| Group 2 | Acetazolamide Low Dose | Experimental: Acetazolamide 62.5 mg twice daily~Acetazolamide: Administration of low dose acetazolamide | 7 | 38 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Participants With Side Effects
- Description
The typical side effects of acetazolamide will be measured daily (paresthesias of fingers and toes, change in urination frequency, and change in taste of beverages).~The side effect questionnaire included the following questions: In the past 12 h, have you experienced the following symptoms: Tingling of toes? Tingling of fingers? Increase in urination? Taste change of beverages? Symptoms were self-reported and rated on a 0-5 scale (0=none, 5=maximum)
- Time frame
- 12 days
- Population
- These participants had sufficient data to be included in the analysis.
Source ClinicalTrials.gov
Trial
- Title
- Acetazolamide for the Prevention of High Altitude Illness: a Comparison of Dosing
- NCT number
- NCT01993667
- Phases
- PHASE4
- Conditions
- Prophylaxis of Acute Mountain Sickness
- Interventions
- Low Dose Acetazolamide, Normal Dose Acetazolamide
- Lead sponsor
- University of Utah
- Results first posted
- 2019-01-29
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01993667?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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