In-home HPV Screening vs Usual Care: Number of Participants With an Abnormal Screening Result
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.0226 | 0.0199 | 0.0257 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.0115 | 0.0096 | 0.0138 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | 0.0111 | 0.00749 | 0.0147 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 1.96 | 1.57 | 2.45 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 1.98 | 1.58 | 2.49 | log | ClinicalTrials.gov | |
| Number needed to treat, for one more participant with the outcome on In-home HPV Screening than on Usual Care | 90.4 | 67.9 | 134 | from the risk difference interval | ClinicalTrials.gov |
Groups 2
Group 2 names the comparator: usual care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | In-home HPV Screening | Usual care PLUS a mailed in-home high-risk HPV testing kit (accompanied by an invitational letter, research information sheet, and illustrated instructions for using the kit). Usual care consists of patient-, provider-, clinic- and systems-level services to promote adherence to Pap screening, including an annual birthday letter with Pap screening reminders, telephone outreach from primary care providers, and automatic alerts in the electronic medical record for overdue women.~Mailed in-home high-risk HPV testing kit~Usual care | 225 | 9,960 | OG000 | ClinicalTrials.gov |
| Group 2 | Usual Care | Usual care. Usual care consists of patient-, provider-, clinic- and systems-level services to promote adherence to Pap screening, including an annual birthday letter with Pap screening reminders, telephone outreach from primary care providers, and automatic alerts in the electronic medical record for overdue women.~Usual care | 114 | 9,891 | OG001 | ClinicalTrials.gov |
Outcome 5
| Field | Value | Source |
|---|---|---|
| Type | SECONDARY | ClinicalTrials.gov |
| Title | Number of Participants With an Abnormal Screening Result | ClinicalTrials.gov |
| Description | Screening result that warrants repeat testing, surveillance, or immediate colposcopy (per current guidelines) before returning to a routine screening schedule~Using an intent-to-treat approach, we will use log-binomial regression to estimate the relative risk for an abnormal screening result for the in-home HPV screening arm versus the usual care arm. | ClinicalTrials.gov |
| Time frame | Assessed for up to 6 months post-randomization | ClinicalTrials.gov |
| Population | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Randomized Trial of In-Home Cervical Cancer Screening in Underscreened Women | ClinicalTrials.gov |
| NCT number | NCT02005510 | ClinicalTrials.gov |
| Phases | NA | ClinicalTrials.gov |
| Conditions | Cervical Cancer | ClinicalTrials.gov |
| Interventions | Mailed in-home high-risk HPV testing kit, Usual care | ClinicalTrials.gov |
| Lead sponsor | University of Washington | ClinicalTrials.gov |
| Results first posted | 2020-09-16 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT02005510?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.