Comparison · NCT02008292-deaths
Healthy Controls for 1210010989 vs Healthy Smoker Controls for 1210010989: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Healthy Controls for 1210010989 vs Healthy Smoker Controls for 1210010989: deaths from any cause. Trial comparisons, record NCT02008292-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02008292-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0 | 0 | 0.082 | wilson | |
| Risk in group 2 | 0 | 0 | 0.0941 | wilson | |
| Risk difference, group 1 minus group 2 | 0 | -0.0941 | 0.082 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | log | a group has no participants with the outcome | |||
| Odds ratio, group 1 over group 2 | log | a cell of the two-by-two table is zero | |||
| Number needed to harm | from the risk difference interval | the two groups' risks are equal |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Healthy Controls for 1210010989 | men and women aged 18-60 years who are able to read and write who are able to give voluntary written informed consent have no current uncontrolled medical condition such as neurological, cardiovascular, endocrine, renal, liver, or thyroid pathology have no history of a neurological or psychiatric disorder (DSMIV Axis 1 and 2) other than schizophrenia in schizophrenia subgroup have not regularly used any prescription, herbal or illegal psychotropic medications (e.g.~antidepressants, antipsychotics, anxiolytics, ecstasy) in the past 6 months (controls) that in the PI's determination puts the subject at increased risk or interferes with the study outcome. Subjects with schizophrenia have not used any herbal or illegal substances in the past 6 months (medication inclusion listed below in Aim 5) drink less than \<21 drinks/week for women and less than \<35 drinks per week for men have not used marijuana in the past 30 days and have not met criteria for dependence in the past 2 years If female, not pregnant or breast feeding If female of childbearing age, must use an acceptable method of birth control, as determined by the principal investigator do not suffer from claustrophobia or any MR contradictions willing to donate blood for genetic studies willing to be followed up monthly after study participation via phone or email contact | 0 | 43 | EG000 |
| Group 2 | Healthy Smoker Controls for 1210010989 | men and women aged 18-60 years who are able to read and write who are able to give voluntary written informed consent have no current uncontrolled medical condition such as neurological, cardiovascular, endocrine, renal, liver, or thyroid pathology have no history of a neurological or psychiatric disorder (DSMIV Axis 1 and 2) other than schizophrenia in schizophrenia subgroup have not regularly used any prescription, herbal or illegal psychotropic medications (e.g.~antidepressants, antipsychotics, anxiolytics, ecstasy) in the past 6 months (controls) that in the PI's determination puts the subject at increased risk or interferes with the study outcome. Subjects with schizophrenia have not used any herbal or illegal substances in the past 6 months (medication inclusion listed below in Aim 5) drink less than \<21 drinks/week for women and less than \<35 drinks per week for men have not used marijuana in the past 30 days and have not met criteria for dependence in the past 2 years If female, not pregnant or breast feeding If female of childbearing age, must use an acceptable method of birth control, as determined by the principal investigator do not suffer from claustrophobia or any MR contradictions willing to donate blood for genetic studies willing to be followed up monthly after study participation via phone or email contact | 0 | 37 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
Source ClinicalTrials.gov
Trial
- Title
- Acetylcholine, Tobacco Smoking, Genes and Nicotinic Receptors
- NCT number
- NCT02008292
- Phases
- NA
- Conditions
- Smoking, Schizophrenia
- Interventions
- Physostigmine
- Lead sponsor
- Yale University
- Results first posted
- 2023-02-06
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02008292?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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