Comparison · NCT02008773-sae
Valacyclovir vs Placebo: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Valacyclovir vs Placebo: serious adverse events. Trial comparisons, record NCT02008773-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02008773-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0357 | 0.0122 | 0.0998 | wilson | |
| Risk in group 2 | 0.0465 | 0.0182 | 0.114 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0108 | -0.0819 | 0.0593 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.768 | 0.177 | 3.33 | log | |
| Odds ratio, group 1 over group 2 | 0.759 | 0.165 | 3.5 | log | |
| Number needed to treat, for one fewer participant with a serious adverse event on Valacyclovir than on Placebo | 92.6 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Valacyclovir | 3000mg daily oral 16 weeks~Valacyclovir HCI 500 mg tablets: Valacyclovir HCI 500 mg capsules 6/day oral for 16 weeks | 3 | 84 | EG000 |
| Group 2 | Placebo | placebo 6 capsules daily oral 16 weeks~placebo: placebo capsules 6/day oral for 16 weeks | 4 | 86 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- Adverse event data were collected throughout the course of subject participation in the 16 week study.
Source ClinicalTrials.gov
Trial
- Title
- A Double-Blind Trial of Adjunctive Valacyclovir to Improve Cognition in Early Phase Schizophrenia
- NCT number
- NCT02008773
- Phases
- PHASE2
- Conditions
- Schizophrenia
- Interventions
- Valacyclovir HCI 500 mg tablets, placebo
- Lead sponsor
- Indiana University
- Results first posted
- 2019-01-30
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02008773?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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