Comparison · NCT02065791-sae
Canagliflozin 100 mg vs Placebo: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Canagliflozin 100 mg vs Placebo: serious adverse events. Trial comparisons, record NCT02065791-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02065791-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.335 | 0.316 | 0.355 | wilson | |
| Risk in group 2 | 0.367 | 0.347 | 0.387 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0319 | -0.06 | -0.00365 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.913 | 0.842 | 0.99 | log | |
| Odds ratio, group 1 over group 2 | 0.869 | 0.768 | 0.984 | log | |
| Number needed to treat, for one fewer participant with a serious adverse event on Canagliflozin 100 mg than on Placebo | 31.4 | 16.7 | 274 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Canagliflozin 100 mg | Participants received canagliflozin 100 milligram (mg) orally once daily. | 737 | 2,200 | EG001 |
| Group 2 | Placebo | Participants received matching placebo orally once daily. | 806 | 2,197 | EG000 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- Up to 4.6 years
Source ClinicalTrials.gov
Trial
- Title
- Evaluation of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Participants With Diabetic Nephropathy
- NCT number
- NCT02065791
- Phases
- PHASE3
- Conditions
- Diabetes Mellitus, Type 2, Diabetic Nephropathy
- Interventions
- Canagliflozin, Placebo
- Lead sponsor
- Janssen Research & Development, LLC
- Results first posted
- 2019-11-20
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02065791?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
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GET https://conductscience.org/api/comparisons/v1/NCT02065791-sae