Comparison · NCT02106975-deaths
Ascorbic Acid vs 5% Dextrose in Water: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Ascorbic Acid vs 5% Dextrose in Water: deaths from any cause. Trial comparisons, record NCT02106975-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02106975-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.298 | 0.21 | 0.402 | wilson | |
| Risk in group 2 | 0.458 | 0.355 | 0.564 | wilson | |
| Risk difference, group 1 minus group 2 | -0.16 | -0.298 | -0.0133 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.65 | 0.434 | 0.973 | log | |
| Odds ratio, group 1 over group 2 | 0.502 | 0.265 | 0.948 | log | |
| Number needed to treat, for one fewer death from any cause on Ascorbic Acid than on 5% Dextrose in Water | 6.24 | 3.36 | 75.4 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Ascorbic Acid | 200mg/kg/day divided over 4 doses. Administered every 6 hours for 96 hours~Ascorbic Acid: Intervention | 25 | 84 | EG000 |
| Group 2 | 5% Dextrose in Water | 50ml every 6 hours for 96 hours~Placebo: 5% Dextrose in water: Placebo | 38 | 83 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
Source ClinicalTrials.gov
Trial
- Title
- Vitamin C Infusion for Treatment in Sepsis Induced Acute Lung Injury
- NCT number
- NCT02106975
- Phases
- PHASE2
- Conditions
- Acute Lung Injury, Sepsis
- Interventions
- Ascorbic Acid, Placebo: 5% Dextrose in water
- Lead sponsor
- Virginia Commonwealth University
- Results first posted
- 2019-10-15
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02106975?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
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