Comparison · NCT02108171-ff26cf1e
Dexmedetomidine vs Placebo: Patients With Postoperative Nausea in Two Groups
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Dexmedetomidine vs Placebo: Patients With Postoperative Nausea in Two Groups. Trial comparisons, record NCT02108171-ff26cf1e. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02108171-ff26cf1e
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.025 | 0.00443 | 0.129 | wilson | |
| Risk in group 2 | 0.0732 | 0.0252 | 0.194 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0482 | -0.171 | 0.0662 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.342 | 0.0371 | 3.15 | log | |
| Odds ratio, group 1 over group 2 | 0.325 | 0.0323 | 3.26 | log | |
| Number needed to treat, for one fewer participant with the outcome on Dexmedetomidine than on Placebo | 20.8 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Dexmedetomidine | intranasal dexmedetomidine~Dexmedetomidine: intranasal dexmedetomidine 1μg.kg-1，0.9% saline was added to make a final volume of 1 mL.all patients received intranasal medication at approximately 45-60 min before induction of anesthesia. | 1 | 40 | OG000 |
| Group 2 | Placebo | intranasal saline~placebo: 0.9% saline 1 mL all patients received intranasal medication at approximately 45-60 min before induction of anesthesia. | 3 | 41 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- OTHER_PRE_SPECIFIED
- Title
- Patients With Postoperative Nausea in Two Groups
- Description
- Patients With postoperative nausea in Two Groups. Nausea or vomiting was treated with 4 mg of intravenous ondansetron.
- Time frame
- 1 day
- Population
Source ClinicalTrials.gov
Trial
- Title
- Intranasal Dexmedetomidine Premedication
- NCT number
- NCT02108171
- Phases
- NA
- Conditions
- Benign Neoplasm of Vocal Fold - Glottis
- Interventions
- Dexmedetomidine, placebo
- Lead sponsor
- Guangzhou First People's Hospital
- Results first posted
- 2016-03-14
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02108171?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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