Comparison · NCT02130986-sae
Procalcitonin (PCT) Group vs Usual Care Group: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Procalcitonin (PCT) Group vs Usual Care Group: serious adverse events. Trial comparisons, record NCT02130986-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02130986-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0169 | 0.0101 | 0.0282 | wilson | |
| Risk in group 2 | 0.0108 | 0.00572 | 0.0205 | wilson | |
| Risk difference, group 1 minus group 2 | 0.00611 | -0.0057 | 0.0185 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.56 | 0.68 | 3.59 | log | |
| Odds ratio, group 1 over group 2 | 1.57 | 0.677 | 3.65 | log | |
| Number needed to harm, for one more participant with a serious adverse event on Procalcitonin (PCT) Group than on Usual Care Group | 164 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: usual care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Procalcitonin (PCT) Group | Procalcitonin (PCT)~Results of procalcitonin level provided to treating clinician (initial in the ED, 6-24 hrs after initial. and Day 3, 5, 7 if in hospital AND on abx or at the treating clinician's discretion)~Telephone Visit at Day 15 and Day 30 to collect ABX days, post-d/c resource use and AQ-20 questionnaire~Bio-bank samples collected in ED for storage at Coordinating Center | 14 | 826 | EG000 |
| Group 2 | Usual Care Group | Usual Care~Telephone Visit at Day 15 and Day 30 to collect ABX days, post-d/c resource use and AQ-20 questionnaire~Bio-bank samples collected in ED for storage at Coordinating Center | 9 | 830 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- By day 30.
Source ClinicalTrials.gov
Trial
- Title
- Procalcitonin Antibiotic Consensus Trial (ProACT)
- NCT number
- NCT02130986
- Phases
- NA
- Conditions
- Lower Respiratory Tract Infection (LRTI)
- Interventions
- Procalcitonin level, Results of procalcitonin (PCT) level to treating clinician, Provide procalcitonin guideline to treating clinician, Telephone Visit
- Lead sponsor
- University of Pittsburgh
- Results first posted
- 2019-01-15
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02130986?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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