Comparison · NCT02148705-3a1facc3
NexoBrid Gel vs Standard of Care (SOC): Secondary Endpoint: Number of Participants With Surgical Excision Performed or Eschar Removal for NexoBrid vs SOC (FAS)
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. NexoBrid Gel vs Standard of Care (SOC): Secondary Endpoint: Number of Participants With Surgical Excision Performed or Eschar Removal for NexoBrid vs SOC (FAS). Trial comparisons, record NCT02148705-3a1facc3. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02148705-3a1facc3
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.04 | 0.0137 | 0.111 | wilson | |
| Risk in group 2 | 0.72 | 0.61 | 0.809 | wilson | |
| Risk difference, group 1 minus group 2 | -0.68 | -0.773 | -0.549 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.0556 | 0.0182 | 0.17 | log | |
| Odds ratio, group 1 over group 2 | 0.0162 | 0.0046 | 0.0571 | log | |
| Number needed to treat, for one fewer participant with the outcome on NexoBrid Gel than on Standard of Care (SOC) | 1.47 | 1.29 | 1.82 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: standard of care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | NexoBrid Gel | NexoBrid Gel is applied to the burn wound at a dose of 2 g NexoBrid sterile powder mixed with 20g sterile Gel Vehicle per 1% of TBSA (\~ surface of an adult palm) for four hours.~NexoBrid | 3 | 75 | OG000 |
| Group 2 | Standard of Care (SOC) | Subjects in the SOC group may be treated with a combination of surgical and non-surgical eschar removal procedures, according to the investigator's judgment.~Standard of Care (SOC) | 54 | 75 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Secondary Endpoint: Number of Participants With Surgical Excision Performed or Eschar Removal for NexoBrid vs SOC (FAS)
- Description
Comparison of NexoBrid over SOC in number of Participants with surgical need for excisional eschar removal as measured by an analysis of incidence of surgical eschar removal (tangential/ minor/ avulsion/ Versajet and/or dermabrasion excision).
- Time frame
- Post application (post 2 h soaking) for NexoBrid arm and immediately post surgical excision for SOC arm.
- Population
- Gel arm is not involved in comparison as defined in the statistical analysis plan. Only NexoBrid and SOC
Source ClinicalTrials.gov
Trial
- Title
- A Study to Evaluate the Efficacy and Safety of NexoBrid in Subjects With Thermal Burns
- NCT number
- NCT02148705
- Phases
- PHASE3
- Conditions
- Thermal Burns
- Interventions
- NexoBrid, Standard of Care (SOC), Gel Vehicle
- Lead sponsor
- MediWound Ltd
- Results first posted
- 2023-06-27
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02148705?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
The record is JSON. No key.
GET https://conductscience.org/api/comparisons/v1/NCT02148705-3a1facc3