Comparison · NCT02159976-ca5c026e
Sequential Therapy vs Modified Bismuth Quadruple Therapy: Counts of Participants Whose Drug Compliance is More Than 85%
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Sequential Therapy vs Modified Bismuth Quadruple Therapy: Counts of Participants Whose Drug Compliance is More Than 85%. Trial comparisons, record NCT02159976-ca5c026e. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02159976-ca5c026e
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.938 | 0.892 | 0.965 | wilson | |
| Risk in group 2 | 0.96 | 0.921 | 0.981 | wilson | |
| Risk difference, group 1 minus group 2 | -0.023 | -0.0732 | 0.0253 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.976 | 0.93 | 1.02 | log | |
| Odds ratio, group 1 over group 2 | 0.618 | 0.234 | 1.63 | log | |
| Number needed to treat, for one fewer participant with the outcome on Sequential Therapy than on Modified Bismuth Quadruple Therapy | 43.6 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Sequential Therapy | pantoprazole 40mg bid 10 days (D1-D10), amoxicillin 1000mg bid 5 days (D1-D5), clarithromycin 500mg bid 5 days (D6-D10), metronidazole 500mg tid 5 days (D6-D10)~Pantoprazole~Amoxicillin~Clarithromycin~Metronidazole | 165 | 176 | OG000 |
| Group 2 | Modified Bismuth Quadruple Therapy | pantoprazole 40mg bid 14 days (D1-D14) , amoxicillin 1000mg bid 14 days (D1-D14), tetracycline 1000mg bid 14 days (D1-D14), bismuth 600mg bid 14 days (D1-D14)~Pantoprazole~Amoxicillin~Tetracycline~Bismuth | 170 | 177 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Counts of Participants Whose Drug Compliance is More Than 85%
- Description
- Time frame
- 4 weeks after termination of eradication therapy, up to 6 weeks
- Population
Source ClinicalTrials.gov
Trial
- Title
- Compare Sequential and Quadruple Therapy for the Eradication of Helicobacter Pylori in Korea
- NCT number
- NCT02159976
- Phases
- NA
- Conditions
- Helicobacter Pylori Infection
- Interventions
- Pantoprazole, Amoxicillin, Clarithromycin, Metronidazole, Tetracycline, Bismuth
- Lead sponsor
- Seoul National University Bundang Hospital
- Results first posted
- 2019-05-13
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02159976?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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