Problem-Solving Therapy vs Health Education: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.156 | 0.104 | 0.226 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.233 | 0.169 | 0.312 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | -0.0775 | -0.172 | 0.0176 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 0.667 | 0.405 | 1.1 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 0.606 | 0.328 | 1.12 | log | ClinicalTrials.gov | |
| Number needed to treat, for one fewer participant with a serious adverse event on Problem-Solving Therapy than on Health Education | 12.9 | from the risk difference interval | the interval includes no difference | ClinicalTrials.gov |
Groups 2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | Problem-Solving Therapy | Problem-Solving Therapy is a treatment approach that teaches patients strategies to address real-life problems.~Problem-Solving Therapy: Problem-Solving Therapy is a treatment approach that teaches patients strategies to address real-life problems. | 21 | 135 | EG000 | ClinicalTrials.gov |
| Group 2 | Health Education | Health education provides didactic information about Gulf War Illness~Health Education: Health Education provides didactic information about Gulf War Illness | 31 | 133 | EG001 | ClinicalTrials.gov |
Harm 2
| Field | Value | Source |
|---|---|---|
| What it counts | Total, serious adverse events | ClinicalTrials.gov |
| Time frame | 9 months | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Cognitive Rehabilitation for Gulf War Illness | ClinicalTrials.gov |
| NCT number | NCT02161133 | ClinicalTrials.gov |
| Phases | NA | ClinicalTrials.gov |
| Conditions | Gulf War Illness | ClinicalTrials.gov |
| Interventions | Problem-Solving Therapy, Health Education | ClinicalTrials.gov |
| Lead sponsor | VA Office of Research and Development | ClinicalTrials.gov |
| Results first posted | 2020-06-04 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT02161133?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.