Comparison · NCT02168855-sae
Active Nicotine Gum vs Inactive Gum: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Active Nicotine Gum vs Inactive Gum: serious adverse events. Trial comparisons, record NCT02168855-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02168855-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0497 | 0.0264 | 0.0918 | wilson | |
| Risk in group 2 | 0.0745 | 0.0449 | 0.121 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0247 | -0.0769 | 0.0267 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.668 | 0.296 | 1.5 | log | |
| Odds ratio, group 1 over group 2 | 0.65 | 0.274 | 1.54 | log | |
| Number needed to treat, for one fewer participant with a serious adverse event on Active Nicotine Gum than on Inactive Gum | 40.4 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Active Nicotine Gum | active nicotine gum: 2 mg, standard over-the-counter nicotine replacement therapy gum~Standard behavioral therapy: Standard behavioral therapy for smoking cessation | 9 | 181 | EG000 |
| Group 2 | Inactive Gum | Standard behavioral therapy: Standard behavioral therapy for smoking cessation | 14 | 188 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
Data for adverse events was collected over the period of time during which each participant was enrolled and participating in the study. For participants completing the entire study, this period would be approximately 26 weeks - i.e., during the 2 weeks during which baseline data was collected, and the 24 weeks that began with their quit date and continued on for the following 6 months.
Source ClinicalTrials.gov
Trial
- Title
- Cessation in Non-Daily Smokers
- NCT number
- NCT02168855
- Phases
- NA
- Conditions
- Smoking
- Interventions
- active nicotine gum, Standard behavioral therapy
- Lead sponsor
- Brian Primack
- Results first posted
- 2020-05-06
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02168855?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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