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Comparison · NCT02297815-eb9a5d30

Narrow Spectrum Antibiotic vs Broad Spectrum Antibiotic: Missed School or Daycare From Illness

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Narrow Spectrum Antibiotic vs Broad Spectrum Antibiotic: Missed School or Daycare From Illness. Trial comparisons, record NCT02297815-eb9a5d30. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02297815-eb9a5d30

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.420.3920.448wilson
Risk in group 20.4340.3980.471wilson
Risk difference, group 1 minus group 2-0.015-0.06110.0309newcombe hybrid score
Risk ratio, group 1 over group 20.9660.8671.08log
Odds ratio, group 1 over group 20.9410.7791.14log
Number needed to treat, for one fewer participant with the outcome on Narrow Spectrum Antibiotic than on Broad Spectrum Antibiotic66.9from the risk difference intervalthe interval includes no difference

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Narrow Spectrum AntibioticChildren diagnosed with an ARTI and prescribed a narrow-spectrum antibiotic5031,199OG000
Group 2Broad Spectrum AntibioticChildren diagnosed with an ARTI and prescribed a broad spectrum antibiotic305702OG001

Outcome

Type
SECONDARY
Title
Missed School or Daycare From Illness
Description
Among children who attend school or daycare, child had to miss school or day care due to illness
Time frame
5-10 days after ARTI diagnosis
Population
Among children who attend school or daycare; 41 children missing race and ethnicity were excluded

Source ClinicalTrials.gov

Trial

Title
Comparative Effectiveness of Antibiotics for Respiratory Infections
NCT number
NCT02297815
Phases
Conditions
Acute Otitis Media, Acute Sinusitis, Group A Streptococcal Pharyngitis
Interventions
Broad-spectrum antibiotics, Narrow-spectrum antibiotics
Lead sponsor
Children's Hospital of Philadelphia
Results first posted
2017-12-08

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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