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Comparison · NCT02322892-72dcc1f8

Thiamine vs Control Arm: Patients With Post-operative Complications

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Thiamine vs Control Arm: Patients With Post-operative Complications. Trial comparisons, record NCT02322892-72dcc1f8. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02322892-72dcc1f8

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.5160.3480.68wilson
Risk in group 20.4850.3250.648wilson
Risk difference, group 1 minus group 20.0313-0.2030.26newcombe hybrid score
Risk ratio, group 1 over group 21.060.6521.74log
Odds ratio, group 1 over group 21.130.4253.02log
Number needed to treat, for one more participant with the outcome on Thiamine than on Control Arm32from the risk difference intervalthe interval includes no difference

Groups2

Group 2 names the comparator: control.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Thiamine200 mg thiamine in 50 mL normal saline solution~Thiamine: 200 mg thiamine in 50 mL normal saline once immediately before surgery and once immediately after (at arrival in the intensive care unit)1631OG001
Group 2Control Arm50 mL normal saline solution~Normal saline solution: 50 mL normal saline once immediately before surgery and once immediately after (at arrival in the intensive care unit)1633OG000

Outcome

Type
SECONDARY
Title
Patients With Post-operative Complications
Description
Atrial fibrillation, delirium, renal failure, stroke, myocardial infarction, acute respiratory distress syndrome, infection
Time frame
Until hospital discharge, limit 60 days
Population

Source ClinicalTrials.gov

Trial

Title
Thiamine as an Adjunctive Therapy in Cardiac Surgery
NCT number
NCT02322892
Phases
PHASE2
Conditions
Coronary Artery Bypass, Cardiac Surgical Procedures
Interventions
Thiamine, Normal saline solution
Lead sponsor
Beth Israel Deaconess Medical Center
Results first posted
2017-03-30

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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