Comparison · NCT02342275-2a2e332f
Propranolol vs Atenolol: The Primary Outcome Measure Was Any Response at 6 Months
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Propranolol vs Atenolol: The Primary Outcome Measure Was Any Response at 6 Months. Trial comparisons, record NCT02342275-2a2e332f. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02342275-2a2e332f
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.937 | 0.893 | 0.964 | wilson | |
| Risk in group 2 | 0.925 | 0.878 | 0.955 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0117 | -0.0414 | 0.0656 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.01 | 0.958 | 1.07 | log | |
| Odds ratio, group 1 over group 2 | 1.2 | 0.54 | 2.67 | log | |
| Number needed to treat, for one more participant with the outcome on Propranolol than on Atenolol | 85.4 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Propranolol | Propranolol~Propranolol: Initiated at a dosage of 1 mg/kg per day divided 3 times daily for 1 week, and then increased to 2 mg/kg per day divided 3 times daily from weeks 2 to 24. | 178 | 190 | OG000 |
| Group 2 | Atenolol | Atenolol~Atenolol: Initiated at a dosage of 0.5 mg/kg per day in a single dose for 1 week, and then increased to 1 mg/kg per day in a single dose from weeks 2 to 24. | 173 | 187 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- The Primary Outcome Measure Was Any Response at 6 Months
- Description
Changes in IH size and color were classified as a complete response, nearly complete response, partial response or no response. The primary outcome measure was any response at 6 months in the intention-to-treat population of all patients who underwent randomization. The any response included compete, nearly complete and partial responses.~A complete response was defined as no redundant tissue or telangiectasia was identified.~A nearly complete response was defined as a minimal degree of telangiectasis, erythema and skin thickening.~A partial response was defined as a size reduction or change in color that did not meet the nearly complete resolution criteria.
- Time frame
- 6 month
- Population
Source ClinicalTrials.gov
Trial
- Title
- Efficacy and Safety of Propranolol Versus Atenolol on the Proliferative Phase of Infantile Hemangioma
- NCT number
- NCT02342275
- Phases
- PHASE3
- Conditions
- Hemangioma
- Interventions
- Propranolol, Atenolol
- Lead sponsor
- West China Hospital
- Results first posted
- 2022-06-16
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02342275?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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