Intervention Arm vs Placebo Arm: Fetal Outcome 1 - Incidence of Early Preterm Delivery (<34 Weeks)
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.0327 | 0.0284 | 0.0376 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.0399 | 0.0351 | 0.0453 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | -0.0072 | -0.0141 | -0.000374 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 0.819 | 0.678 | 0.99 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 0.813 | 0.669 | 0.989 | log | ClinicalTrials.gov | |
| Number needed to treat, for one fewer participant with the outcome on Intervention Arm than on Placebo Arm | 139 | 71.1 | 2,680 | from the risk difference interval | ClinicalTrials.gov |
Groups 2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | Intervention Arm | Daily administration of low dose (81 mg) aspirin \[also known as acetylsalicylic acid (ASA\], initiated between 6 0/7 weeks and 13 6/7 weeks GA and continued to 36 0/7 weeks GA. | 189 | 5,780 | OG000 | ClinicalTrials.gov |
| Group 2 | Placebo Arm | Identical appearing placebo beginning between 6 0/7 weeks and 13 6/7 weeks GA and continuing until 36 0/7 weeks GA or delivery. | 230 | 5,764 | OG001 | ClinicalTrials.gov |
Outcome 5
| Field | Value | Source |
|---|---|---|
| Type | OTHER_PRE_SPECIFIED | ClinicalTrials.gov |
| Title | Fetal Outcome 1 - Incidence of Early Preterm Delivery (<34 Weeks) | ClinicalTrials.gov |
| Description | \- Early preterm delivery (\<34 weeks) | ClinicalTrials.gov |
| Time frame | At delivery | ClinicalTrials.gov |
| Population | Modified ITT; numbers reported reflect available data and therefore do not always reflect the total population defined in the mITT | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN) | ClinicalTrials.gov |
| NCT number | NCT02409680 | ClinicalTrials.gov |
| Phases | NA | ClinicalTrials.gov |
| Conditions | Premature Birth | ClinicalTrials.gov |
| Interventions | Low dose aspirin, Placebo | ClinicalTrials.gov |
| Lead sponsor | NICHD Global Network for Women's and Children's Health | ClinicalTrials.gov |
| Results first posted | 2021-09-08 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT02409680?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.