Comparison · NCT02426125-2867a074
Ramucirumab + Docetaxel vs Placebo + Docetaxel: Number of Participants With Anti-Ramucirumab Antibodies
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Ramucirumab + Docetaxel vs Placebo + Docetaxel: Number of Participants With Anti-Ramucirumab Antibodies. Trial comparisons, record NCT02426125-2867a074. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02426125-2867a074
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0151 | 0.00514 | 0.0434 | wilson | |
| Risk in group 2 | 0.0376 | 0.0192 | 0.0723 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0225 | -0.0587 | 0.0113 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.401 | 0.108 | 1.49 | log | |
| Odds ratio, group 1 over group 2 | 0.392 | 0.103 | 1.5 | log | |
| Number needed to treat, for one fewer participant with the outcome on Ramucirumab + Docetaxel than on Placebo + Docetaxel | 44.5 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Ramucirumab + Docetaxel | Ramucirumab (10 mg/kg) IV plus docetaxel (75 mg/m²) IV on day 1 of each 21-day cycle. Participants may continue to receive treatment until discontinuation criteria are met. | 3 | 199 | OG000 |
| Group 2 | Placebo + Docetaxel | Placebo IV plus docetaxel (75 mg/m²) IV on day 1 of each 21-day cycle. Participants may continue to receive treatment until discontinuation criteria are met. | 8 | 213 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Participants With Anti-Ramucirumab Antibodies
- Description
- Number of participants with positive treatment emergent anti-ramucirumab antibodies was summarized by treatment group.
- Time frame
- 29.7 Months
- Population
- All randomized participants who received at least one dose of study drug at baseline and post-baseline.
Source ClinicalTrials.gov
Trial
- Title
- A Study of Ramucirumab (LY3009806) Plus Docetaxel in Participants With Urothelial Cancer
- NCT number
- NCT02426125
- Phases
- PHASE3
- Conditions
- Urothelial Carcinoma
- Interventions
- Ramucirumab, Docetaxel, Placebo
- Lead sponsor
- Eli Lilly and Company
- Results first posted
- 2019-03-08
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02426125?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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