Prioritized Clinical Decision Support vs Usual Care: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.159 | 0.148 | 0.17 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.174 | 0.163 | 0.185 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | -0.0152 | -0.0307 | 0.000197 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 0.912 | 0.831 | 1 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 0.896 | 0.801 | 1 | log | ClinicalTrials.gov | |
| Number needed to treat, for one fewer participant with a serious adverse event on Prioritized Clinical Decision Support than on Usual Care | 65.6 | from the risk difference interval | the interval includes no difference | ClinicalTrials.gov |
Groups 2
Group 2 names the comparator: usual care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | Prioritized Clinical Decision Support | Patients and providers were presented with patient-specific written advice as to prioritized treatment and lifestyle changes that could reduce their cardiovascular risk, prompted by an electronic health record based alert during their primary care visits. | 722 | 4,550 | EG000 | ClinicalTrials.gov |
| Group 2 | Usual Care | Patients and providers were not presented with the prioritized clinical decision support. | 763 | 4,387 | EG001 | ClinicalTrials.gov |
Harm 2
| Field | Value | Source |
|---|---|---|
| What it counts | Total, serious adverse events | ClinicalTrials.gov |
| Time frame | The adverse event data was collected on the date of the after-index visit and every subsequent visit through the end of the intervention period on September 19, 2018. | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Reducing Cardiovascular Risk in Adults With Serious Mental Illness | ClinicalTrials.gov |
| NCT number | NCT02451670 | ClinicalTrials.gov |
| Phases | NA | ClinicalTrials.gov |
| Conditions | Chronic Disease, Mental Disorder, Health Behavior, Bipolar Disorder, Schizophrenia | ClinicalTrials.gov |
| Interventions | Prioritized Clinical Decision Support | ClinicalTrials.gov |
| Lead sponsor | HealthPartners Institute | ClinicalTrials.gov |
| Results first posted | 2019-11-05 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT02451670?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.