Comparison · NCT02508194-deaths
Placebo + IIV vs MEDI7510+IIV: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Placebo + IIV vs MEDI7510+IIV: deaths from any cause. Trial comparisons, record NCT02508194-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02508194-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.00527 | 0.00225 | 0.0123 | wilson | |
| Risk in group 2 | 0.00317 | 0.00108 | 0.00928 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0021 | -0.00471 | 0.00942 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.66 | 0.399 | 6.94 | log | |
| Odds ratio, group 1 over group 2 | 1.67 | 0.397 | 6.99 | log | |
| Number needed to harm, for one more death from any cause on Placebo + IIV than on MEDI7510+IIV | 476 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Placebo + IIV | Participants received a single IM injection of placebo (matched with MEDI7510) in one arm and single IM injection of IIV in the contralateral arm. | 5 | 948 | EG000 |
| Group 2 | MEDI7510+IIV | Participants received a single IM injection of MEDI7510 in one arm and single IM injection of IIV in the contralateral arm. | 3 | 946 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
- Day 1 (post-dose) through end of Season 1 (approximately 1 year)
Source ClinicalTrials.gov
Trial
- Title
- A Study to Evaluate the Efficacy of MEDI7510 in Older Adults
- NCT number
- NCT02508194
- Phases
- PHASE2
- Conditions
- Respiratory Syncytial Virus
- Interventions
- MEDI7510, IIV, Placebo
- Lead sponsor
- MedImmune LLC
- Results first posted
- 2017-12-20
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02508194?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
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