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Comparison · NCT02603328-e3955db5

Treatment vs Placebo: Compare Rate of Drug Compliance in Atorvastatin vs Placebo Group

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Treatment vs Placebo: Compare Rate of Drug Compliance in Atorvastatin vs Placebo Group. Trial comparisons, record NCT02603328-e3955db5. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02603328-e3955db5

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 110.8961wilson
Risk in group 210.891wilson
Risk difference, group 1 minus group 20-0.1040.11newcombe hybrid score
Risk ratio, group 1 over group 2111log
Odds ratio, group 1 over group 2loga cell of the two-by-two table is zero
Number needed to treatfrom the risk difference intervalthe two groups' risks are equal

Groups2

Group 2 names the comparator: placebo.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1TreatmentAtorvastatin 80mg OD (optimal dose). Treatment dose will be de-escalated to 40mg based on reported adverse events.~Atorvastatin: 40-80 mg OD3333OG000
Group 2PlaceboIdentically looking capsules containing no active ingredient~Placebo: inactive3131OG001

Outcome

Type
SECONDARY
Title
Compare Rate of Drug Compliance in Atorvastatin vs Placebo Group
Description
Compare number of subjects with 90% or greater protocol compliance throughout the 2 year follow-up period
Time frame
2 years of follow-up
Population

Source ClinicalTrials.gov

Trial

Title
Atorvastatin Treatment of Cavernous Angiomas With Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial
NCT number
NCT02603328
Phases
PHASE1, PHASE2
Conditions
Cerebral Cavernous Malformation
Interventions
Atorvastatin, Placebo
Lead sponsor
University of Chicago
Results first posted
2025-08-22

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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