Comparison · NCT02632786-deaths
NEOD001 24 mg/kg vs Placebo: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. NEOD001 24 mg/kg vs Placebo: deaths from any cause. Trial comparisons, record NCT02632786-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02632786-deaths
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0455 | 0.0156 | 0.125 | wilson | |
| Risk in group 2 | 0.0952 | 0.0444 | 0.193 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0498 | -0.152 | 0.0449 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.477 | 0.125 | 1.83 | log | |
| Odds ratio, group 1 over group 2 | 0.452 | 0.108 | 1.89 | log | |
| Number needed to treat, for one fewer death from any cause on NEOD001 24 mg/kg than on Placebo | 20.1 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | NEOD001 24 mg/kg | 24 mg/kg IV every 4 weeks for 12 months | 3 | 66 | EG000 |
| Group 2 | Placebo | 0.9% Saline IV every 4 weeks for 12 months | 6 | 63 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
- Initiation of study drug through the last study visit or up to 30 days after date of last dose, whichever is later
Source ClinicalTrials.gov
Trial
- Title
- The PRONTO Study, a Global Phase 2b Study of NEOD001 in Previously Treated Subjects With Light Chain (AL) Amyloidosis
- NCT number
- NCT02632786
- Phases
- PHASE2
- Conditions
- AL Amyloidosis
- Interventions
- NEOD001, Placebo
- Lead sponsor
- Prothena Biosciences Ltd.
- Results first posted
- 2019-04-05
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02632786?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
The record is JSON. No key.
GET https://conductscience.org/api/comparisons/v1/NCT02632786-deaths