Comparison · NCT02639182-deaths
AGS-16C3F vs Axitinib: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. AGS-16C3F vs Axitinib: deaths from any cause. Trial comparisons, record NCT02639182-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02639182-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.537 | 0.419 | 0.651 | wilson | |
| Risk in group 2 | 0.667 | 0.547 | 0.768 | wilson | |
| Risk difference, group 1 minus group 2 | -0.129 | -0.285 | 0.0363 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.806 | 0.609 | 1.07 | log | |
| Odds ratio, group 1 over group 2 | 0.581 | 0.288 | 1.17 | log | |
| Number needed to treat, for one fewer death from any cause on AGS-16C3F than on Axitinib | 7.73 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | AGS-16C3F | Participants received 1.8 mg/kg of AGS-16C3F once every three weeks by single (60-minute) IV infusion. | 36 | 67 | EG000 |
| Group 2 | Axitinib | Participants received axitinib at a starting dose of 5 mg orally twice daily and then adjusted to 2 to 10 mg orally twice daily, as defined in the product label and per local institutional guidelines. | 44 | 66 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
- From first dose up to 53 months
Source ClinicalTrials.gov
Trial
- Title
- A Study of AGS-16C3F vs. Axitinib in Metastatic Renal Cell Carcinoma
- NCT number
- NCT02639182
- Phases
- PHASE2
- Conditions
- Metastatic Renal Cell Carcinoma
- Interventions
- AGS-16C3F, Axitinib
- Lead sponsor
- Astellas Pharma Global Development, Inc.
- Results first posted
- 2020-09-23
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02639182?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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