Comparison · NCT02688270-c8f0f8a8
Vascana vs Vehicle Cream: Raynaud's Symptom Severity (Percentage of Responders)
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Vascana vs Vehicle Cream: Raynaud's Symptom Severity (Percentage of Responders). Trial comparisons, record NCT02688270-c8f0f8a8. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02688270-c8f0f8a8
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.569 | 0.448 | 0.682 | wilson | |
| Risk in group 2 | 0.446 | 0.332 | 0.567 | wilson | |
| Risk difference, group 1 minus group 2 | 0.123 | -0.0476 | 0.284 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.28 | 0.905 | 1.8 | log | |
| Odds ratio, group 1 over group 2 | 1.64 | 0.82 | 3.28 | log | |
| Number needed to treat, for one more participant with the outcome on Vascana than on Vehicle Cream | 8.13 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: vehicle.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Vascana | Vascana (0.9% nitroglycerin cream): Study drug administered topically | 37 | 65 | OG000 |
| Group 2 | Vehicle Cream | Vehicle Cream (placebo): Vehicle administered topically | 29 | 65 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Raynaud's Symptom Severity (Percentage of Responders)
- Description
- Time frame
- 6 weeks
- Population
Source ClinicalTrials.gov
Trial
- Title
- Efficacy and Safety of Vascana® in Subjects With Secondary Raynaud's Phenomenon
- NCT number
- NCT02688270
- Phases
- PHASE2
- Conditions
- Raynaud's Phenomenon Secondary to Connective Tissue Disease
- Interventions
- Vascana (0.9% nitroglycerin cream), Vehicle Cream (placebo)
- Lead sponsor
- Covis Pharma S.à.r.l.
- Results first posted
- 2022-11-02
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02688270?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
The record is JSON. No key.
GET https://conductscience.org/api/comparisons/v1/NCT02688270-c8f0f8a8