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Comparison · NCT02709018-sae

Losartan vs Placebo: serious adverse events

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Losartan vs Placebo: serious adverse events. Trial comparisons, record NCT02709018-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02709018-sae

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.02670.007340.0921wilson
Risk in group 20.01350.002390.0727wilson
Risk difference, group 1 minus group 20.0132-0.04910.0795newcombe hybrid score
Risk ratio, group 1 over group 21.970.18321.3log
Odds ratio, group 1 over group 220.17722.5log
Number needed to harm, for one more participant with a serious adverse event on Losartan than on Placebo76from the risk difference intervalthe interval includes no difference

Groups2

Group 2 names the comparator: placebo.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1LosartanLosartan flexibly dosed from 25-100 mg per day over 10 weeks~losartan: Angiotensin receptor blocker (ARB)275EG000
Group 2PlaceboPlacebo flexibly dosed from 25-100 mg per day over 10 weeks~Placebo: Placebo174EG001

Harm

What it counts
Total, serious adverse events
Time frame
10 Weeks (Study Duration)

Source ClinicalTrials.gov

Trial

Title
A Controlled Trial of Losartan in Posttraumatic Stress Disorder
NCT number
NCT02709018
Phases
NA
Conditions
Posttraumatic Stress Disorder
Interventions
losartan, Placebo
Lead sponsor
University of California, San Diego
Results first posted
2021-03-12

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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