Comparison · NCT02713386-d79e5653
Arm I (Paclitaxel and Carboplatin) vs Arm II (Ruxolitinib, Paclitaxel, and Carboplatin): Number of Patients Who Have Total Gross Resection (Phase II)
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Arm I (Paclitaxel and Carboplatin) vs Arm II (Ruxolitinib, Paclitaxel, and Carboplatin): Number of Patients Who Have Total Gross Resection (Phase II). Trial comparisons, record NCT02713386-d79e5653. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02713386-d79e5653
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.571 | 0.409 | 0.72 | wilson | |
| Risk in group 2 | 0.636 | 0.525 | 0.735 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0649 | -0.255 | 0.121 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.898 | 0.644 | 1.25 | log | |
| Odds ratio, group 1 over group 2 | 0.762 | 0.337 | 1.72 | log | |
| Number needed to treat, for one fewer participant with the outcome on Arm I (Paclitaxel and Carboplatin) than on Arm II (Ruxolitinib, Paclitaxel, and Carboplatin) | 15.4 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Arm I (Paclitaxel and Carboplatin) | See Detailed Description.~Carboplatin: Given IV~Paclitaxel: Given IV~Therapeutic Conventional Surgery: Undergo TRS | 20 | 35 | OG000 |
| Group 2 | Arm II (Ruxolitinib, Paclitaxel, and Carboplatin) | See Detailed Description.~Carboplatin: Given IV~Paclitaxel: Given IV~Ruxolitinib Phosphate: Given PO~Therapeutic Conventional Surgery: Undergo TRS | 49 | 77 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Patients Who Have Total Gross Resection (Phase II)
- Description
- The outcome is whether there is a total gross resection rate at time of interval cytoreductive surgery among those who had surgery.
- Time frame
- At the time of surgery (surgery occurred within 6 weeks after completion of cycle 3, as soon as nadir counts permit and surgery deemed safe by investigator)
- Population
- Eligible
Source ClinicalTrials.gov
Trial
- Title
- Ruxolitinib Phosphate, Paclitaxel, and Carboplatin in Treating Patients With Stage III-IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
- NCT number
- NCT02713386
- Phases
- PHASE1, PHASE2
- Conditions
Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube High Grade Serous Adenocarcinoma, FIGO Stage III Ovarian Cancer 2014, FIGO Stage IIIA Ovarian Cancer 2014, FIGO Stage IIIA1 Ovarian Cancer, FIGO Stage IIIA2 Ovarian Cancer, FIGO Stage IIIB Ovarian Cancer 2014, FIGO Stage IIIC Ovarian Cancer 2014, FIGO Stage IVA Ovarian Cancer 2014, FIGO Stage IVB Ovarian Cancer 2014, Ovarian Clear Cell Adenocarcinoma, Ovarian Endometrioid Adenocarcinoma, Ovarian High Grade Serous Adenocarcinoma, Primary Peritoneal Endometrioid Adenocarcinoma, Primary Peritoneal High Grade Serous Adenocarcinoma, Stage III Fallopian Tube Cancer AJCC v7, Stage III Primary Peritoneal Cancer AJCC v7, Stage IIIA Fallopian Tube Cancer AJCC v7, Stage IIIA Primary Peritoneal Cancer AJCC v7, Stage IIIB Fallopian Tube Cancer AJCC v7, Stage IIIB Primary Peritoneal Cancer AJCC v7, Stage IIIC Fallopian Tube Cancer AJCC v7, Stage IIIC Primary Peritoneal Cancer AJCC v7, Stage IV Fallopian Tube Cancer AJCC v6 and v7, Stage IV Primary Peritoneal Cancer AJCC v7
- Interventions
- Carboplatin, Paclitaxel, Ruxolitinib Phosphate, Therapeutic Conventional Surgery
- Lead sponsor
- NRG Oncology
- Results first posted
- 2024-10-24
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02713386?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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