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Comparison · NCT02713529-deaths

AMG 820 1100 MG vs AMG 820 1400 MG: deaths from any cause

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. AMG 820 1100 MG vs AMG 820 1400 MG: deaths from any cause. Trial comparisons, record NCT02713529-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02713529-deaths

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.1220.07150.202wilson
Risk in group 20.05560.009880.258wilson
Risk difference, group 1 minus group 20.0669-0.1410.159newcombe hybrid score
Risk ratio, group 1 over group 22.20.30515.9log
Odds ratio, group 1 over group 22.370.28919.5log
Number needed to harm, for one more death from any cause on AMG 820 1100 MG than on AMG 820 1400 MG14.9from the risk difference intervalthe interval includes no difference

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1AMG 820 1100 MGIncludes participants from all treatment arms that were administered AMG 820 1100 mg.1298EG000
Group 2AMG 820 1400 MGIncludes participants from all treatment arms that were administered AMG 820 1400 mg.118EG001

Harm

What it counts
Total, all-cause mortality
Time frame
The TEAE timeframe was Day 1 up to 207 days for Part 1 and Day 1 up to 572 days for Part 2. The median time frame is 122 days.

Source ClinicalTrials.gov

Trial

Title
Safety and Efficacy Study of AMG 820 and Pembrolizumab Combination in Select Advanced Solid Tumor Cancer
NCT number
NCT02713529
Phases
PHASE1, PHASE2
Conditions
Pancreatic Cancer, Colorectal Cancer, Non-Small Cell Lung Cancer
Interventions
AMG820 and pembrolizumab
Lead sponsor
AmMax Bio, Inc.
Results first posted
2020-06-01

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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