Electronic AKI Alert vs Usual Care: Composite of Progression of AKI, Inpatient Dialysis, or Inpatient Death
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.213 | 0.199 | 0.228 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.209 | 0.195 | 0.224 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | 0.00411 | -0.0165 | 0.0247 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 1.02 | 0.925 | 1.12 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 1.02 | 0.906 | 1.16 | log | ClinicalTrials.gov | |
| Number needed to treat, for one more participant with the outcome on Electronic AKI Alert than on Usual Care | 243 | from the risk difference interval | the interval includes no difference | ClinicalTrials.gov |
Groups 2
Group 2 names the comparator: usual care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | Electronic AKI Alert | A pop-up alert will fire when a provider opens the electronic health record of a patient with AKI until such time as AKI is documented in the problem list, or AKI resolves.~AKI Alert: Provider's will receive a pop-up alert in the electronic health record until AKI is documented in the problem list or AKI resolves. | 653 | 3,059 | OG001 | ClinicalTrials.gov |
| Group 2 | Usual Care | No alert will be fired. | 622 | 2,971 | OG000 | ClinicalTrials.gov |
Outcome 5
| Field | Value | Source |
|---|---|---|
| Type | PRIMARY | ClinicalTrials.gov |
| Title | Composite of Progression of AKI, Inpatient Dialysis, or Inpatient Death | ClinicalTrials.gov |
| Description | Progression of AKI is defined by an increase in KDIGO creatinine stage from that present at the time of randomization.~Dialysis is defined by the receipt of hemodialysis, continuous renal replacement therapy or peritoneal dialysis. Isolated ultrafiltration treatments (for the purpose of volume removal) will not be included.~Mortality will be determined from hospital administrative records. | ClinicalTrials.gov |
| Time frame | 14 days from randomization | ClinicalTrials.gov |
| Population | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Optimizing Electronic Alerts for Acute Kidney Injury | ClinicalTrials.gov |
| NCT number | NCT02753751 | ClinicalTrials.gov |
| Phases | NA | ClinicalTrials.gov |
| Conditions | Acute Kidney Injury | ClinicalTrials.gov |
| Interventions | AKI Alert | ClinicalTrials.gov |
| Lead sponsor | Yale University | ClinicalTrials.gov |
| Results first posted | 2022-02-10 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT02753751?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.