Comparison · NCT02759120-7970b7df
Antimicrobial Therapy Plus Standard of Care vs Standard of Care: Number of Participants With First Non-elective, Respiratory Hospitalization or All-cause Mortality
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Antimicrobial Therapy Plus Standard of Care vs Standard of Care: Number of Participants With First Non-elective, Respiratory Hospitalization or All-cause Mortality. Trial comparisons, record NCT02759120-7970b7df. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02759120-7970b7df
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.205 | 0.16 | 0.259 | wilson | |
| Risk in group 2 | 0.216 | 0.17 | 0.27 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0115 | -0.0819 | 0.0592 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.947 | 0.677 | 1.32 | log | |
| Odds ratio, group 1 over group 2 | 0.933 | 0.61 | 1.43 | log | |
| Number needed to treat, for one fewer participant with the outcome on Antimicrobial Therapy Plus Standard of Care than on Standard of Care | 87 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: standard of care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Antimicrobial Therapy Plus Standard of Care | Co-trimoxazole OR doxycycline~Antimicrobial therapy: Co-trimoxazole or Doxycycline: 160mg trimethoprim/800mg sulfamethoxazole (double strength co-trimoxazole) twice daily plus folic acid 5 mg daily OR doxycycline 100mg once daily if weight \< 50 kilograms or 100mg twice daily if weight \> 50 kilograms for up to 36 months | 52 | 254 | OG000 |
| Group 2 | Standard of Care | Standard of care for patients with IPF for comparison~No Intervention: Standard of Care: Standard of care | 56 | 259 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Number of Participants With First Non-elective, Respiratory Hospitalization or All-cause Mortality
- Description
- Time frame
- Randomization to up to 35 months
- Population
Source ClinicalTrials.gov
Trial
- Title
- CleanUP IPF for the Pulmonary Trials Cooperative
- NCT number
- NCT02759120
- Phases
- PHASE3
- Conditions
- Idiopathic Pulmonary Fibrosis
- Interventions
- Antimicrobial therapy: Co-trimoxazole or Doxycycline, No Intervention: Standard of Care
- Lead sponsor
- Weill Medical College of Cornell University
- Results first posted
- 2021-03-03
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02759120?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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