Comparison · NCT02771977-11e026fc
Drug-specific Alert vs Usual Care: Percentage of Patients for Whom Any One of the Targeted Medications is Discontinued
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Drug-specific Alert vs Usual Care: Percentage of Patients for Whom Any One of the Targeted Medications is Discontinued. Trial comparisons, record NCT02771977-11e026fc. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02771977-11e026fc
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.611 | 0.592 | 0.63 | wilson | |
| Risk in group 2 | 0.559 | 0.54 | 0.578 | wilson | |
| Risk difference, group 1 minus group 2 | 0.052 | 0.0249 | 0.0791 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.09 | 1.04 | 1.15 | log | |
| Odds ratio, group 1 over group 2 | 1.24 | 1.11 | 1.39 | log | |
| Number needed to treat, for one more participant with the outcome on Drug-specific Alert than on Usual Care | 19.2 | 12.6 | 40.2 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: usual care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Drug-specific Alert | A drug-specific AKI alert, including information about the drug of interest as well as the presence of AKI will be fired.~Drug-specific alert: A drug-specific alert, informing the provider of the presence of AKI as well as recent exposure to a potentially nephrotoxic agent, will be fired. | 1,547 | 2,532 | OG001 |
| Group 2 | Usual Care | No alert will be fired. | 1,413 | 2,528 | OG000 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Percentage of Patients for Whom Any One of the Targeted Medications is Discontinued
- Description
The Percentage of patients for whom the targeted agent was discontinued within 24 hours from randomization. For individuals with active orders for more than one targeted agent, cessation of any will be adequate to meet this endpoint.
- Time frame
- Assessed within 24 hours from randomization
- Population
Source ClinicalTrials.gov
Trial
- Title
- Drug-Targeted Alerts for Acute Kidney Injury
- NCT number
- NCT02771977
- Phases
- NA
- Conditions
- Acute Kidney Injury
- Interventions
- Drug-specific alert
- Lead sponsor
- Yale University
- Results first posted
- 2023-06-29
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02771977?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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