Comparison · NCT02786277-0980e437
Recommended vs Anti-recommended: Proportion of Patients With Progression to a Higher Stage of AKI OR Dialysis OR Death
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Recommended vs Anti-recommended: Proportion of Patients With Progression to a Higher Stage of AKI OR Dialysis OR Death. Trial comparisons, record NCT02786277-0980e437. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02786277-0980e437
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.19 | 0.167 | 0.215 | wilson | |
| Risk in group 2 | 0.185 | 0.162 | 0.21 | wilson | |
| Risk difference, group 1 minus group 2 | 0.00475 | -0.029 | 0.0386 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.03 | 0.856 | 1.23 | log | |
| Odds ratio, group 1 over group 2 | 1.03 | 0.826 | 1.29 | log | |
| Number needed to treat, for one more participant with the outcome on Recommended than on Anti-recommended | 210 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Recommended | Those whose uplift score represents a probability of benefit greater than 0.5 will generate an alert, while those whose uplift score represents a probability of benefit less than 0.5 will not generate an alert.~Alert: An alert informing the provider of the presence of acute kidney injury will be fired. | 190 | 1,002 | OG000 |
| Group 2 | Anti-recommended | Those whose uplift score represents a probability of benefit greater than 0.5 will not generate an alert, while those whose uplift score represents a probability of benefit less than 0.5 will generate an alert.~Alert: An alert informing the provider of the presence of acute kidney injury will be fired. | 193 | 1,044 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Proportion of Patients With Progression to a Higher Stage of AKI OR Dialysis OR Death
- Description
Progression of AKI is defined as the increase in KDIGO stage from the time of randomization to the present. For patients who are discharged, we will impute 14-day creatinine using the last observation carried forward method.~Dialysis is defined as the receipt of hemodialysis, continuous renal replacement therapy, or peritoneal dialysis. Isolated ultrafiltration treatments will not be included.~Mortality will be determined from hospital administrative records.
- Time frame
- Within 14 days from randomization
- Population
Source ClinicalTrials.gov
Trial
- Title
- Learning Alerts for Acute Kidney Injury
- NCT number
- NCT02786277
- Phases
- NA
- Conditions
- Acute Kidney Injury
- Interventions
- Alert
- Lead sponsor
- Yale University
- Results first posted
- 2025-10-08
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02786277?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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