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Comparison · NCT02786277-52bacb87

Recommended vs Anti-recommended: Progression to Stage 3 AKI

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Recommended vs Anti-recommended: Progression to Stage 3 AKI. Trial comparisons, record NCT02786277-52bacb87. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02786277-52bacb87

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.07190.05740.0895wilson
Risk in group 20.06320.050.0796wilson
Risk difference, group 1 minus group 20.00864-0.01320.0307newcombe hybrid score
Risk ratio, group 1 over group 21.140.8231.57log
Odds ratio, group 1 over group 21.150.8121.62log
Number needed to treat, for one more participant with the outcome on Recommended than on Anti-recommended116from the risk difference intervalthe interval includes no difference

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Recommended
Those whose uplift score represents a probability of benefit greater than 0.5 will generate an alert, while those whose uplift score represents a probability of benefit less than 0.5 will not generate an alert.~Alert: An alert informing the provider of the presence of acute kidney injury will be fired.
721,002OG000
Group 2Anti-recommended
Those whose uplift score represents a probability of benefit greater than 0.5 will not generate an alert, while those whose uplift score represents a probability of benefit less than 0.5 will generate an alert.~Alert: An alert informing the provider of the presence of acute kidney injury will be fired.
661,044OG001

Outcome

Type
SECONDARY
Title
Progression to Stage 3 AKI
Description
Progression to Stage 3 AKI is defined as a tripling of serum creatinine between the date of randomization and 14 days post randomization, and is considered a worsening of AKI.
Time frame
Assessed from the date of randomization to 14 days post randomization
Population

Source ClinicalTrials.gov

Trial

Title
Learning Alerts for Acute Kidney Injury
NCT number
NCT02786277
Phases
NA
Conditions
Acute Kidney Injury
Interventions
Alert
Lead sponsor
Yale University
Results first posted
2025-10-08

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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