Comparison · NCT02791763-542dc567
Daprodustat in ND Participants vs Epoetin Beta Pegol in ND Participants: Number of ND Participants Who Had an Hgb Level of Less Than 7.5 g/dL
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Daprodustat in ND Participants vs Epoetin Beta Pegol in ND Participants: Number of ND Participants Who Had an Hgb Level of Less Than 7.5 g/dL. Trial comparisons, record NCT02791763-542dc567. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02791763-542dc567
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.00926 | 0.00164 | 0.0506 | wilson | |
| Risk in group 2 | 0 | 0 | 0.034 | wilson | |
| Risk difference, group 1 minus group 2 | 0.00926 | -0.0256 | 0.0506 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | log | a group has no participants with the outcome | |||
| Odds ratio, group 1 over group 2 | log | a cell of the two-by-two table is zero | |||
| Number needed to treat, for one more participant with the outcome on Daprodustat in ND Participants than on Epoetin Beta Pegol in ND Participants | 108 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Daprodustat in ND Participants | Eligible ND participants received oral daprodustat (1, 2, 4, 6, 8, 12, 18 or 24 milligrams \[mg\] as recommended) dose once daily for 52 weeks. | 1 | 108 | OG000 |
| Group 2 | Epoetin Beta Pegol in ND Participants | Eligible ND participants received subcutaneous (SC) epoetin beta pegol (25, 50, 75, 100, 150, 200 or 250 microgram \[µg\] as recommended) dose once every 2 or 4 weeks for 52 weeks. | 0 | 109 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of ND Participants Who Had an Hgb Level of Less Than 7.5 g/dL
- Description
- Number of ND participants who had an Hgb level of less than 7.5 g/dL is presented.
- Time frame
- Up to week 52
- Population
- ITT Population
Source ClinicalTrials.gov
Trial
- Title
- Phase III Study of GSK1278863 in Japanese Non-dialysis (ND) and Peritoneal Dialysis (PD) Subjects With Renal Anemia
- NCT number
- NCT02791763
- Phases
- PHASE3
- Conditions
- Anaemia
- Interventions
- 1 to 4 mg tablets of GSK1278863, 6 mg GSK1278863 tablet, Epoetin beta pegol
- Lead sponsor
- GlaxoSmithKline
- Results first posted
- 2019-11-13
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02791763?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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