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Comparison · NCT02827500-b29d7d19

Pre-discharge Ivabradine vs Usual Care: Number of Patients With Heart Rate <70 Bpm at 180 Days

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Pre-discharge Ivabradine vs Usual Care: Number of Patients With Heart Rate <70 Bpm at 180 Days. Trial comparisons, record NCT02827500-b29d7d19. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02827500-b29d7d19

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.3850.2650.52wilson
Risk in group 20.2120.1220.34wilson
Risk difference, group 1 minus group 20.173-0.002890.335newcombe hybrid score
Risk ratio, group 1 over group 21.820.9713.4log
Odds ratio, group 1 over group 22.330.9775.55log
Number needed to treat, for one more participant with the outcome on Pre-discharge Ivabradine than on Usual Care5.78from the risk difference intervalthe interval includes no difference

Groups2

Group 2 names the comparator: usual care.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Pre-discharge IvabradineActive Comparator: ivabradine~ivabradine: Active Comparator: ivabradine2052OG001
Group 2Usual CarePlacebo Comparator: usual care~Usual Care: Placebo Comparator: usual care1152OG000

Outcome

Type
SECONDARY
Title
Number of Patients With Heart Rate <70 Bpm at 180 Days
Description
Time frame
180 days
Population

Source ClinicalTrials.gov

Trial

Title
Predischarge Initiation of Ivabradine in the Management of Heart Failure (PRIME-HF)
NCT number
NCT02827500
Phases
PHASE4
Conditions
Heart Failure
Interventions
ivabradine, Usual Care
Lead sponsor
Duke University
Results first posted
2019-10-01

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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