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Comparison · NCT02827500-dc8cf236

Pre-discharge Ivabradine vs Usual Care: Number of Participants Taking Ivabradine at 180 Days

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Pre-discharge Ivabradine vs Usual Care: Number of Participants Taking Ivabradine at 180 Days. Trial comparisons, record NCT02827500-dc8cf236. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02827500-dc8cf236

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.4040.2820.539wilson
Risk in group 20.1150.0540.23wilson
Risk difference, group 1 minus group 20.2880.1210.437newcombe hybrid score
Risk ratio, group 1 over group 23.51.547.96log
Odds ratio, group 1 over group 25.191.8814.3log
Number needed to treat, for one more participant with the outcome on Pre-discharge Ivabradine than on Usual Care3.472.298.26from the risk difference interval

Groups2

Group 2 names the comparator: usual care.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Pre-discharge IvabradineActive Comparator: ivabradine~ivabradine: Active Comparator: ivabradine2152OG001
Group 2Usual CarePlacebo Comparator: usual care~Usual Care: Placebo Comparator: usual care652OG000

Outcome

Type
PRIMARY
Title
Number of Participants Taking Ivabradine at 180 Days
Description
Time frame
180 days
Population
Intent to treat population

Source ClinicalTrials.gov

Trial

Title
Predischarge Initiation of Ivabradine in the Management of Heart Failure (PRIME-HF)
NCT number
NCT02827500
Phases
PHASE4
Conditions
Heart Failure
Interventions
ivabradine, Usual Care
Lead sponsor
Duke University
Results first posted
2019-10-01

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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