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Comparison · NCT02829957-8d6b31eb

Rivaroxaban vs Apixaban: Number of Participants Who Crossed Over to Another Anticoagulant

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Rivaroxaban vs Apixaban: Number of Participants Who Crossed Over to Another Anticoagulant. Trial comparisons, record NCT02829957-8d6b31eb. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02829957-8d6b31eb

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.3750.1370.694wilson
Risk in group 20.09090.01620.377wilson
Risk difference, group 1 minus group 20.284-0.08840.612newcombe hybrid score
Risk ratio, group 1 over group 24.130.5232.8log
Odds ratio, group 1 over group 260.4973.5log
Number needed to treat, for one more participant with the outcome on Rivaroxaban than on Apixaban3.52from the risk difference intervalthe interval includes no difference

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1RivaroxabanRivaroxaban: 15mg BID for 7 days, then 20mg daily for three months38OG000
Group 2ApixabanApixaban: 10mg BID for 7 days, then 5mg BID for three months111OG001

Outcome

Type
SECONDARY
Title
Number of Participants Who Crossed Over to Another Anticoagulant
Description
Time frame
3 months
Population

Source ClinicalTrials.gov

Trial

Title
RAMBLE - Rivaroxaban vs. Apixaban for Heavy Menstrual Bleeding
NCT number
NCT02829957
Phases
PHASE2, PHASE3
Conditions
Venous Thromboembolism, Menstruation
Interventions
Apixaban, Rivaroxaban
Lead sponsor
Indiana University
Results first posted
2023-05-10

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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