Comparison · NCT02839343-deaths
Arm 1 (mFOLFIRINOX + Surgery + FOLFOX) vs Arm 2 (mFOLFIRINOX + Radiation + Surgery + FOLFOXx): deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Arm 1 (mFOLFIRINOX + Surgery + FOLFOX) vs Arm 2 (mFOLFIRINOX + Radiation + Surgery + FOLFOXx): deaths from any cause. Trial comparisons, record NCT02839343-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02839343-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.636 | 0.516 | 0.742 | wilson | |
| Risk in group 2 | 0.473 | 0.347 | 0.602 | wilson | |
| Risk difference, group 1 minus group 2 | 0.164 | -0.0132 | 0.328 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.35 | 0.964 | 1.88 | log | |
| Odds ratio, group 1 over group 2 | 1.95 | 0.941 | 4.05 | log | |
| Number needed to harm, for one more death from any cause on Arm 1 (mFOLFIRINOX + Surgery + FOLFOX) than on Arm 2 (mFOLFIRINOX + Radiation + Surgery + FOLFOXx) | 6.11 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Arm 1 (mFOLFIRINOX + Surgery + FOLFOX) | Patients receive 8 cycles of mFOLFIRINOX. One cycle is 14 days. mFOLFIRINOX consists of oxaliplatin, irinotecan, leucovorin and 5-FU. Patients undergo surgery and receive 4 cycles of FOLFOX 4-12 weeks after surgery. FOLFOX consists of oxaliplatin, leucovorin and 5-FU. | 42 | 66 | EG000 |
| Group 2 | Arm 2 (mFOLFIRINOX + Radiation + Surgery + FOLFOXx) | Patients receive 7 cycles of mFOLFIRINOX. One cycle is 14 days. mFOLFIRINOX consists of oxaliplatin, irinotecan, leucovorin and 5-FU. Patients receive radiation therapy then undergo surgery and receive 4 cycles of FOLFOX 4-12 weeks after surgery. FOLFOX consists of oxaliplatin, leucovorin and 5-FU. | 26 | 55 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
- Adverse events and Serious Adverse events were collected for 2 years and all cause mortality was collected for 4 years and 7 months.
Source ClinicalTrials.gov
Trial
- Title
- Combination Chemotherapy With or Without Hypofractionated Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer
- NCT number
- NCT02839343
- Phases
- PHASE2
- Conditions
- Pancreatic Adenocarcinoma, Borderline Resectable Adenocarcinoma of the Head of the Pancrease
- Interventions
- radiation therapy, surgery, mFOLFIRINOX, FOLFOX
- Lead sponsor
- Alliance for Clinical Trials in Oncology
- Results first posted
- 2022-05-24
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02839343?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
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GET https://conductscience.org/api/comparisons/v1/NCT02839343-deaths