5ARI Users vs Non 5ARI Users: Suicide Attempt (Based on Administrative Data Elements From National Ambulatory Care Reporting System, and Ontario Regional Mental Health Database)
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.00181 | 0.00156 | 0.00211 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.00139 | 0.00117 | 0.00166 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | 0.000418 | 0.0000547 | 0.000786 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 1.3 | 1.03 | 1.63 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 1.3 | 1.03 | 1.63 | log | ClinicalTrials.gov | |
| Number needed to treat, for one more participant with the outcome on 5ARI Users than on Non 5ARI Users | 2,390 | 1,270 | 18,300 | from the risk difference interval | ClinicalTrials.gov |
Groups 2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | 5ARI Users | 5ARI: Exposure to finasteride/dutasteride | 169 | 93,197 | OG000 | ClinicalTrials.gov |
| Group 2 | Non 5ARI Users | 130 | 93,197 | OG001 | ClinicalTrials.gov |
Outcome 5
| Field | Value | Source |
|---|---|---|
| Type | SECONDARY | ClinicalTrials.gov |
| Title | Suicide Attempt (Based on Administrative Data Elements From National Ambulatory Care Reporting System, and Ontario Regional Mental Health Database) | ClinicalTrials.gov |
| Description | 1. NACRS: presentation to the emergency room: ICD 10 codes X60-X84 (intentional self harm).~2. OMHRS: admission with suicide ideation.~i. Self injury attempts: D1A or selfinjury\_attempt=3, 4, 5, or 6 ii. Self injury intent: D1B or selfinjury\_intent=1 iii. Self injury considered: D1C or selfinjury\_cons=3, 4, 5 or 6 iv. Self injury plan: D1DB or suicide\_plan=1 | ClinicalTrials.gov |
| Time frame | Through study completition, an average of 18 months. | ClinicalTrials.gov |
| Population | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | 5 Alpha Reductase Inhibitors And The Risk Of Suicide And Depression | ClinicalTrials.gov |
| NCT number | NCT02876757 | ClinicalTrials.gov |
| Phases | ClinicalTrials.gov | |
| Conditions | BPH, Depression, Suicide | ClinicalTrials.gov |
| Interventions | 5ARI | ClinicalTrials.gov |
| Lead sponsor | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | ClinicalTrials.gov |
| Results first posted | 2018-02-05 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT02876757?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.