Comparison · NCT02884908-sae
Pregabalin + BBCET vs Placebo + BBCET: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Pregabalin + BBCET vs Placebo + BBCET: serious adverse events. Trial comparisons, record NCT02884908-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02884908-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0385 | 0.00682 | 0.189 | wilson | |
| Risk in group 2 | 0.0556 | 0.00988 | 0.258 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0171 | -0.222 | 0.14 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.692 | 0.0463 | 10.4 | log | |
| Odds ratio, group 1 over group 2 | 0.68 | 0.0398 | 11.6 | log | |
| Number needed to treat, for one fewer participant with a serious adverse event on Pregabalin + BBCET than on Placebo + BBCET | 58.5 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Pregabalin + BBCET | This group will be comprised of subjects with the NI/I/II type who receive study medication (Pregabalin) and Brief Behavioral Compliance Enhancement Treatment (BBCET).~Pregabalin plus BBCET: Medication; BBCET = Brief Behavioral Compliance Enhancement Treatment | 1 | 26 | EG000 |
| Group 2 | Placebo + BBCET | This group will be comprised of subjects with the NI/I/II type who receive placebo and Brief Behavioral Compliance Enhancement Treatment (BBCET).~Placebo plus BBCET: Placebo; BBCET = Brief Behavioral Compliance Enhancement Treatment | 1 | 18 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- 14 weeks
Source ClinicalTrials.gov
Trial
- Title
- Pharmacogenetic Treatment With Anti-Glutaminergic Agents for Comorbid PTSD & AUD
- NCT number
- NCT02884908
- Phases
- PHASE3
- Conditions
- PTSD, Alcohol Use Disorder
- Interventions
- Pregabalin plus BBCET, Placebo plus BBCET
- Lead sponsor
- University of Maryland, Baltimore
- Results first posted
- 2024-03-13
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02884908?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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