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Comparison · NCT02927249-deaths

Arm I (Aspirin) vs Arm II (Placebo): deaths from any cause

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Arm I (Aspirin) vs Arm II (Placebo): deaths from any cause. Trial comparisons, record NCT02927249-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02927249-deaths

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.03180.0240.0419wilson
Risk in group 20.02850.02120.0381wilson
Risk difference, group 1 minus group 20.00329-0.009080.0157newcombe hybrid score
Risk ratio, group 1 over group 21.120.7441.67log
Odds ratio, group 1 over group 21.120.7371.7log
Number needed to harm, for one more death from any cause on Arm I (Aspirin) than on Arm II (Placebo)304from the risk difference intervalthe interval includes no difference

Groups2

Group 2 names the comparator: placebo.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Arm I (Aspirin)Patients receive aspirin PO QD for five years in the absence of disease progression or unacceptable toxicity.481,511EG000
Group 2Arm II (Placebo)Patients receive placebo PO QD for five years in the absence of disease progression or unacceptable toxicity.431,510EG001

Harm

What it counts
Total, all-cause mortality
Time frame
5 years

Source ClinicalTrials.gov

Trial

Title
Aspirin in Preventing Recurrence of Cancer in Patients With HER2 Negative Stage II-III Breast Cancer After Chemotherapy, Surgery, and/or Radiation Therapy
NCT number
NCT02927249
Phases
PHASE3
Conditions
Node Positive HER2 Negative Breast Cancer
Interventions
Placebo, Aspirin
Lead sponsor
Alliance for Clinical Trials in Oncology
Results first posted
2023-03-27

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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